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Ocvir V 400/100mg 28’s Tablets (Sofosbuvir)

Ocvir V contains sofosbuvir which is now available in Pakistan at Jasmeds. The price range of the Ocvir V tablet is Rs 7,000/- to Rs 15,000/-.

Product Description

Brand: Ocvir V
Form: Tablet
Strength: 400/100 mg
Size: 28’s Tablets
Active Ingredient: Sofosbuvir + velpatasvir
Manufacturer: Sami Pharmaceuticals

Original price was: ₨ 11,000.Current price is: ₨ 9,000.

Description

Uses of the Ocvir V 400/100 mg Tablets 

Ocvir V 400/100 mg tablets, containing sofosbuvir (400mg) and velpatasvir (100mg), are primarily used to treat chronic hepatitis C virus (HCV) infection in adults. This combination is effective against all six major HCV genotypes.

Primary Uses:

Treatment of Chronic Hepatitis C:

Ocvir V is used to stop the replication of the hepatitis C virus in your body, helping to reduce liver damage and improve liver health.

It is effective for treating HCV infection with or without cirrhosis (liver scarring).

Treatment for Patients with Cirrhosis:

For those with compensated cirrhosis (mild liver scarring), Ocvir V is typically used alone.

For those with decompensated cirrhosis (severe liver damage), it is often combined with ribavirin for enhanced effectiveness.

Additional Details

How Does Ocvir V 400 mg Tablet Work? 

Ocvir V 400 mg Tablet is a medication used to treat chronic hepatitis C infection in adults. It contains two active ingredients: sofosbuvir and velpatasvir. These work together to stop the hepatitis C virus (HCV) from multiplying in your body.

Sofosbuvir is a nucleotide analog NS5B polymerase inhibitor. It blocks a protein that the hepatitis C virus needs to make copies of itself.

Velpatasvir is an NS5A inhibitor. It blocks a different protein that the hepatitis C virus needs to reproduce.

How Should You Take Ocvir V 400 mg Tablet?

Follow your doctor’s instructions precisely. 

You can take Ocvir V with or without food, as it does not affect absorption.

Take the tablet at the same time every day to maintain consistent drug levels in your body.

For most patients, the treatment lasts 12 weeks.

If you have decompensated cirrhosis, your doctor may prescribe Ocvir V with ribavirin for 12 weeks.

For most patients, the treatment lasts 12 weeks.

If you have decompensated cirrhosis, your doctor may prescribe Ocvir V with ribavirin for 12 weeks.

Warnings and Precautions of Ocvir V 400/100mg Tablets

Hepatitis B Reactivation:

If you have a history of hepatitis B, taking Epclusa can reactivate the virus. This can lead to severe liver damage or failure.

Your doctor will screen you for hepatitis B before starting treatment and monitor you during and after therapy.

Drug Interactions:

Certain medications can reduce the effectiveness of Epclusa or increase side effects:

Avoid rifampin, carbamazepine, phenobarbital, phenytoin, and St. John’s Wort.

Using amiodarone with Epclusa may cause life-threatening bradycardia (slow heart rate).

Avoid taking antacids or proton pump inhibitors (e.g., omeprazole) within 4 hours of Epclusa, as they can interfere with drug absorption.

Cirrhosis Management: If you have decompensated cirrhosis, your doctor may prescribe Epclusa with ribavirin. Ribavirin carries additional risks, such as anemia, and requires close monitoring.

Pregnancy and Breastfeeding:

Avoid Epclusa with ribavirin during pregnancy, as ribavirin can cause severe birth defects.

Women and men using ribavirin should use effective contraception during treatment and for 6 months afterward.

Limited data exists on Epclusa use during breastfeeding; consult your doctor before use.

Kidney Function: If you have severe kidney impairment or are on dialysis, Epclusa should be used cautiously, as its safety in these cases is not fully established.

Allergic Reactions: Discontinue use and seek immediate medical attention if you experience symptoms such as rash, difficulty breathing, or swelling.

Possible Side Effects of Ocvir 400/100mg Tablets

Ocvir 400/100mg tablets, like other medications, can cause side effects. These vary in severity and frequency. Below is a concise list of possible side effects:

Common Side Effects:

Fatigue:

Feeling unusually tired is reported in approximately 22% of patients.

Headache:

Occurs in about 17% of patients.

Nausea:

Affects approximately 9% of patients.

Less Common Side Effects:

Insomnia:

Difficulty sleeping may occur in some cases.

Irritability:

You might experience mood changes or irritability.

Skin Reactions:

Rash or itching has been reported occasionally.

Serious but Rare Side Effects:

Bradycardia:

Severe slowing of the heart rate, especially when taken with amiodarone.

Symptoms include dizziness, fainting, or extreme fatigue. Seek immediate medical attention if this occurs.

Allergic Reactions:

Severe reactions such as swelling, difficulty breathing, or a rash may require immediate medical care.

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