Xtandi 40mg Capsule

Uses of the Xtandi 40mg Tablets

Here’s a breakdown of its specific uses:

1. Metastatic Hormone-Sensitive Prostate Cancer (mHSPC):

This is prostate cancer that has spread to other parts of the body (metastasized) but still responds to hormone therapy that lowers testosterone (androgen deprivation therapy).
Xtandi is used in combination with androgen deprivation therapy to further improve treatment outcomes.

2. High-Risk Non-Metastatic Castration-Resistant Prostate Cancer (nmCRPC):

This refers to prostate cancer that hasn’t spread but is resistant to treatments that lower testosterone (castration-resistant) and shows signs of a high risk of spreading in the future (based on specific factors like PSA levels and bone scans).
Xtandi is used as a single agent in this context to delay the spread of the cancer.

3. Other Potential Uses:

In some cases, Xtandi might be used after chemotherapy for advanced prostate cancer, but this decision should be made in consultation with a healthcare professional.

How Does Xtandi Work?

It works by blocking the action of male hormones (androgens), such as testosterone, which can help to slow the growth and spread of the cancer. Here’s a breakdown of how it works

1. Targeting Androgens: Prostate cancer cells often rely on androgens to grow and divide. Xtandi belongs to a class of drugs called androgen receptor inhibitors. These drugs work by interfering with the way androgens bind to and activate the androgen receptors in cancer cells.

2. Blocking the Signal: When an androgen binds to an androgen receptor, it sends a signal to the cell to grow and divide. Xtandi acts like a blocker, preventing the androgen from binding to the receptor and stopping the growth signal from being transmitted.

3. Slowing Cancer Growth: As a result of blocking the androgen signal, Xtandi can slow the growth of prostate cancer cells and even cause some of them to die. This can help to delay the progression of the cancer and improve overall survival rates.

How Should You Take Xtandi Tablets?

To take Xtandi tablets, follow these instructions:

Xtandi can be taken with or without food.

Swallow the tablets whole; do not chew, dissolve, or open them. Do not cut, crush, or chew the tablets.

Take your prescribed dose once a day, at the same time each day.

If you miss a dose, take only that day’s prescribed dose. Do not double up on your prescribed dose if you miss a day. Resume taking your prescribed dose at the regular time the following day.