How Does Xgeva 120mg Injection Works?
Xgeva 120mg injection works by targeting a protein called RANKL, which plays a crucial role in bone breakdown. Here’s how it works:
RANKL Inhibition: Xgeva contains denosumab, a monoclonal antibody that binds to RANKL. This prevents RANKL from activating its receptor, RANK, on cells called osteoclasts. Osteoclasts are responsible for breaking down bone tissue.
Reduced Bone Breakdown: By blocking RANKL, Xgeva reduces the activity of osteoclasts. This leads to less bone breakdown and helps to maintain bone density.
Increased Bone Strength: With less bone breakdown, bones become stronger and less prone to fractures. This is particularly important in conditions like osteoporosis, where bones are weakened and brittle.
Treatment of Giant Cell Tumor of Bone: Xgeva is also used to treat giant cell tumor of bone, a rare noncancerous tumor that can destroy bone tissue. By inhibiting RANKL, Xgeva can help to slow down the growth of these tumors.
How Should You Take Xgeva 120mg Works?
Injection Site: Xgeva can be injected into the thigh, abdomen, or upper arm. The healthcare professional will choose the appropriate site and rotate injection sites to minimize skin reactions.
Administration: The healthcare professional will use a sterile needle and syringe to administer the injection. They will clean the injection site with an antiseptic solution and then insert the needle under the skin. The medication will be slowly injected, and the needle will be withdrawn.
Post-Injection Care: After the injection, the healthcare professional may apply gentle pressure to the injection site to prevent bleeding. They will also dispose of the needle and syringe properly.
