Tecentriq Infusion contains Atezolizumab | belongs to
How it works
Tecentriq Infusion (Atezolizumab) 1200 mg/20 mL 1 Vial works as a form of immunotherapy and blocks the activity of programmed death ligand 1 (PDL-1), a molecule found on T cells that suppresses immune activity. By blocking PDL-1, T-cells function better and the immune response is stimulated to find and kill cancer cells.
Dosage
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Missed Dose
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Overdose
Additional Information:
How to use Tecentriq Infusion (Atezolizumab) 1200 mg/20 mL 1 Vial
Administer the initial infusion over 60 mins through an IV line with or without a sterile, nonpyrogenic, low-protein binding in-line filter (pore size: 0.2-0.22 micron). Do not coadminister other drugs through the same IV line. Do not administer as an IV push or bolus.
Reconstitution: To prepare soln for inf, withdraw 20 mL of atezolizumab from the vial. Dilute into a 250 mL polyvinyl chloride (PVC), polyethylene (PE), or polyolefin (PO) infusion bag containing 0.9% Sodium Chloride Injection. Dilute with 0.9% Sodium Chloride Injection only. Mix diluted solution by gentle inversion. Do not shake.
Compatibility: Stable in NS.
Stability: If diluted infusion soln is not used immediately, store soln either at room temp for no more than 6 hrs from the time of preparation. This includes room temp storage of the inf in the inf bag and time for adm of the inf, or under refrigeration at 2°C-8°C for no more than 24 hrs from time of preparation. Do not freeze. Vials: Store vials under refrigeration at 2°C-8°C in original carton to protect from light. Do not freeze. Do not shake.
What are the adverse effects of Tecentriq Infusion (Atezolizumab) 1200 mg/20 mL 1 Vial?
Nausea, vomiting, constipation, diarrhoea, fatigue, pyrexia, myalgia, arthralgia, cough, dyspnoea, peripheral oedema, pruritus, skin rash, decreased appetite, hematuria, UTI. Discontinue treatment in patients with severe infusion reactions.
What happens if I miss a dose of Tecentriq Infusion (Atezolizumab) 1200 mg/20 mL 1 Vial?
Adults: IV: 1200 mg via infusion over 60 mins every 3 wks. Continue until disease progression or unacceptable toxicity. If the first inf is tolerated, all subsequent inf may be delivered over 30 mins. Children: Not recommended.
One of the following licensed pharmacy from the nearest location will deliver Tecentriq Infusion (Atezolizumab) 1200 mg/20 mL 1 Vial. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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