What is Ofev 150mg Capsules?

Ofev 150mg capsules are a prescription medication used to treat certain lung conditions characterized by scarring and stiffening of lung tissue. It contains the active ingredient nintedanib, which belongs to a class of drugs called tyrosine kinase inhibitors.

Can I Buy Ofev 150mg Capsules Online in Pakistan?

Yes, you can buy Ofev 150mg Capsules from Jasmeds, which is a reliable provider of wellness medicines in Pakistan offering 24/7 delivery service.

What Should You Do If You Take an Overdose of Ofev 150mg Capsules?

Yes, Ofev (nintedanib) 150 mg capsules can interact with other medications, and caution is advised when using them together. Here are the key points regarding drug interactions: Known Interactions : There are 249 drugs known to interact with Ofev, including: Major Interactions : 20 drugs can cause significant interactions that should generally be avoided. Moderate Interactions : 229 drugs may have moderate interactions, which require careful monitoring.

Is Ofev 150mg Capsules Safe to Take?

Ofev (nintedanib) 150mg capsules are generally considered safe when prescribed by a doctor for conditions like idiopathic pulmonary fibrosis (IPF), chronic fibrosing interstitial lung diseases (ILDs), or systemic sclerosis-associated ILD.

When is the Best Time to Take Ofev Capsules?

The best time to take Ofev capsules is twice daily, approximately 12 hours apart, with food. This helps reduce the risk of stomach-related side effects. Always follow your doctor’s instructions for the timing and dosage.

Can I stop taking Ofev 150mg Tablet?

You should not stop taking Ofev 150mg tablets without consulting your doctor. Stopping abruptly may worsen your condition. Speak with your healthcare provider if you experience side effects or have concerns about the medication.

Is Ofev 150mg Tablet bad for kidneys?

Ofev (nintedanib) 150mg is not specifically known to be harmful to the kidneys, but it may cause dehydration or increased creatinine levels in some cases due to side effects like diarrhea. Patients with pre-existing kidney conditions should use it cautiously and under medical supervision. Regular monitoring by your doctor is recommended.

Can We Use Other Medicines with Ofev 150mg Capsules?

Yes, Ofev (nintedanib) 150 mg capsules can interact with other medications, and caution is advised when using them together. Here are the key points regarding drug interactions: Known Interactions : There are 249 drugs known to interact with Ofev, including: Major Interactions: 20 drugs can cause significant interactions that should generally be avoided. Moderate Interactions : 229 drugs may have moderate interactions, which require careful monitoring.

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Ofev 150mg (Nintedanib) Capsules

Ofev 150mg capsules contains (nintednib) which is now available in Pakistan at Jasmeds. The price range of the Ofev 150mg Capsules is Rs 135,000 to Rs 300,000/-.

Product Description

Brand: Ofev
Form: Capsules
Packet Size: 60’s Tablets
Active ingredient: Nintednib
Manufacturer: Boehringer Ingelheim
Treatment: Lung Diseases (IPF)

₨ 240,000

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Description

How Does Ofev 150mg Tablet Work?

Ofev (nintedanib) works by blocking the activity of certain enzymes called tyrosine kinases. These enzymes are involved in the formation of scar tissue in the lungs, which is a key factor in the progression of idiopathic pulmonary fibrosis (IPF) and other fibrosing interstitial lung diseases. By blocking these enzymes, Ofev helps to slow down the formation of scar tissue and reduce the decline in lung function.

How Should You Take Ofev 150mg Capsules?

To take Ofev (nintedanib) 150 mg capsules correctly, follow these guidelines:

With Food: Always take Ofev with food to enhance absorption and reduce gastrointestinal side effects.

Missed Dose: If you miss a dose, take it as soon as you remember. However, if it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at once.

Consult Your Doctor: Always follow your healthcare provider’s instructions regarding dosage adjustments or any concerns about side effects. If you experience severe side effects, consult your doctor for possible dose reduction or treatment interruption.

Additional Details

Uses of the Ofev 150mg Capsules

Ofev (nintedanib) 150 mg capsules are primarily used for the treatment of specific chronic lung diseases. Here are the main uses:

Idiopathic Pulmonary Fibrosis (IPF): Ofev is indicated for adults with IPF, a condition characterized by progressive scarring of lung tissue, leading to breathing difficulties. It helps slow the decline in lung function associated with this disease.

Chronic Fibrosing Interstitial Lung Diseases (ILDs): Ofev is also prescribed for chronic ILDs that exhibit a progressive phenotype, which means they worsen over time and are marked by lung fibrosis.

Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD): This medication is utilized to slow the rate of pulmonary function decline in patients suffering from interstitial lung disease related to systemic sclerosis, a condition that causes thickening and scarring of tissues throughout the body.

Recommended Dosage of Ofev 150mg Tablet?

The recommended dosage of Ofev (nintedanib) 150 mg capsules is as follows:

Standard Dosage: Take 150 mg orally twice daily, approximately 12 hours apart. This totals 300 mg per day.

Administration: It should be taken with food and swallowed whole; do not chew, crush, or open the capsules.

Warnings and Precautions For Ofev 150mg Tablet?

Ofev (nintedanib) 150 mg capsules come with several warnings and precautions that patients should be aware of:

Liver Function: Ofev can cause elevated liver enzymes, indicating potential liver injury. Regular monitoring of liver function tests is recommended, especially during the first three months of treatment. Patients should report symptoms like jaundice, dark urine, or abdominal pain.

Gastrointestinal Issues: There is a risk of serious gastrointestinal perforation. Patients should be vigilant for symptoms such as severe abdominal pain or bloating and report these immediately.

Bleeding Risks: Ofev may increase the risk of bleeding events. Patients should notify their healthcare provider if they experience unusual bruising or bleeding12.

Cardiovascular Concerns: The medication can lead to arterial thromboembolic events, including heart attacks and strokes. Signs such as chest pain or sudden weakness should prompt immediate medical attention.

Pregnancy and Contraception: Ofev can cause serious birth defects or fetal death. Effective contraception is essential during treatment and for at least three months after discontinuation. Women should undergo a pregnancy test before starting therapy.

Kidney Issues: Nephrotic range proteinuria has been reported; patients should monitor for signs such as foamy urine or fluid retention and report these to their doctor12.

Smoking: Smoking may reduce the effectiveness of Ofev. Patients are encouraged to quit smoking prior to and during treatment

Drug Interactions: Caution is advised when using nonsteroidal anti-inflammatory drugs (NSAIDs) alongside Ofev, as this combination may increase bleeding risks.

Possible Side Effects of Ofev 150mg Capsules?

Ofev (nintedanib) 150 mg capsules can cause a range of side effects, varying from mild to severe. Here are the key side effects associated with its use:

Common Side Effects:

Diarrhea: Affects approximately 62-76% of patients, often occurring within the first three months of treatment.

Nausea: Reported by about 24-32% of users.

Vomiting: Occurs in about 12-25% of patients.

Abdominal Pain: Affects around 15-18% of users.

Decreased Appetite: Seen in about 9-11% of patients, potentially leading to weight loss.

Headache: Reported by approximately 8-9%.

Fatigue: Affects around 11% of users.

Hypertension: Occurs in about 5-6%, with possible symptoms like headaches or lightheadedness.

Serious Side Effects:

Liver Problems: Elevated liver enzymes (14%) may indicate liver damage; symptoms include dark urine and jaundice.

Gastrointestinal Perforation: Rare but serious, requiring immediate medical attention if severe abdominal pain occurs.

Severe Allergic Reactions: Signs include hives, difficulty breathing, and swelling of the face or throat.

Heart Attack Symptoms: Chest pain or pressure, nausea, and sweating should prompt immediate medical evaluation.

Stroke Symptoms: Sudden numbness or weakness, especially on one side of the body, slurred speech, or vision problems.

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Ofev 150mg (Nintedanib) Capsules

Description

How Does Ofev 150mg Tablet Work?

How Should You Take Ofev 150mg Capsules?

Additional Details

Uses of the Ofev 150mg Capsules

Recommended Dosage of Ofev 150mg Tablet?

Warnings and Precautions For Ofev 150mg Tablet?

Possible Side Effects of Ofev 150mg Capsules?

Customer Reviews

Reviews

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