What is an Ocrevus 300mg Injection?

Ocrevus 300mg Injection is a prescription medication used to treat multiple sclerosis (MS). It is administered as an intravenous infusion by a doctor or a nurse, usually in a hospital or clinic setting.

What Should You Do If You Take an Overdose of Ocrevus 300mg Injection?

Ocrevus is administered by a healthcare professional in a controlled medical setting. It is highly unlikely that you would receive an overdose of Ocrevus. However, if you experience any unusual or concerning symptoms after receiving Ocrevus, it is crucial to inform your doctor or nurse immediately. They are equipped to monitor you during and after the infusion and address any potential side effects or complications promptly.

Can Kidney Patients Use Ocrevus 300mg Injection?

Yes, Ocrevus is generally considered safe for patients with kidney disease. No dose adjustment is recommended for people with kidney problems. However, it's important to discuss your specific situation with your doctor, as they can assess your overall health and determine if Ocrevus is the right treatment option for you.

Can Liver Patients Use Ocrevus 300mg Injection?

No, Ocrevus is not contraindicated for patients with liver disease. However, it is important to note that Ocrevus can cause liver problems, such as hepatitis B reactivation. Therefore, patients with liver disease should be monitored closely for signs and symptoms of liver problems while taking Ocrevus.

Can I Take a Ocrevus 300mg Injection Before Driving?

No, It's best to avoid driving after taking Ocrevus ( Ocrelizumab ) until you know how it affects you. Ocrevus can cause fatigue, dizziness, and seizures in some people. These side effects could impair your ability to drive safely.

Can I Buy Ocrevus 300mg Injection Online in Pakistan?

Yes, you can buy Ocrevus 300mg Injection online in Pakistan from Jasmeds. Which is a reliable provider of wellness medicines in Pakistan offering 24/7 delivery service.

What Medicines Should I Avoid When Taking Ocrevus 300mg Injection?

Here's a concise list of medications to avoid while taking Ocrevus 300mg injection: Live vaccines: Avoid live vaccines like measles, mumps, rubella (MMR), chickenpox, and the nasal spray flu vaccine. Other disease-modifying therapies (DMTs) for multiple sclerosis: Examples include dimethyl fumarate (Tecfidera), glatiramer (Copaxone), and others. Certain monoclonal antibodies: Examples include alemtuzumab (Lemtrada), belimumab (Benlysta), and others. Interferons: Examples include interferon beta-1a (Avonex, Rebif), interferon beta-1b (Betaseron), and others. Corticosteroids: Examples include dexamethasone (Hemady), methylprednisolone (Medrol), and prednisone.

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Ocrevus 300mg/10ml Injection (Ocrelizumab)

Ocrevus 300mg Injection contains Ocrelizumab which is now available in Pakistan at Jasmeds. The price range of the Ocrevus 300mg capsule is Rs 300,000/- to Rs 600,000/-.

Product Description

Brand: Ocrevus

Form: Injection

Size: 1 Vial Injection

Active Ingredient: Ocrelizumab

Manufacturer: Roche

Treatment: Multiple Sclerosis

₨ 500,000

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Description

How Does Ocrevus 300mg Injection Work?

Ocrevus is a medication used to treat multiple sclerosis (MS). It works by targeting and destroying specific immune cells called B cells, which are thought to play a role in the development of MS. By reducing the number of these B cells, Ocrevus helps to reduce inflammation and damage to the nervous system, which can slow the progression of MS and reduce the number of relapses.

How Should You Take Ocrevus 300mg Injection?

Administration: Given as an intravenous (IV) infusion by a healthcare professional.

Dosing Schedule:

Initial Dose: Two 300mg infusions, given two weeks apart.
Maintenance Dose: A single 600mg infusion every six months after the initial doses.
Pre-Medications: Corticosteroids, antihistamines, and antipyretics may be given before infusion to reduce side effects.
Monitoring: Patients are monitored during and after the infusion for potential allergic reactions or infusion-related side effects.

Additional Details

Uses of the Ocrevus 300mg Injection

Multiple Sclerosis (MS): Used to treat relapsing forms of MS (RMS) and primary progressive MS (PPMS) in adults.

Mechanism: Works by targeting and depleting B-cells (CD20+), reducing inflammation and slowing disease progression.

Benefits: Helps prevent relapses, delays disability progression, and reduces new brain lesions in MS patients.

Administration: Given as an intravenous (IV) infusion under medical supervision.

Recommended Dosage of Ocrevus 300mg Injection

Ocrevus (ocrelizumab) is administered as an intravenous (IV) infusion—not as a standalone “300 mg injection.” For treating multiple sclerosis, the dosing regimen is as follows:

Initial Dose:

Step 1: 300 mg IV infusion on Day 1

Step 2: 300 mg IV infusion on Day 15
(This totals 600 mg over the initial treatment cycle.)

Subsequent Doses:

600 mg IV infusion every 6 months

Note: Infusions should be given under medical supervision with appropriate premedications to help manage infusion-related reactions. Always follow the guidance of your healthcare provider and the prescribing information for safe and effective use.

Warnings and Precautions of Ocrevus 300mg Injection

Infusion Reactions – Common and can be serious; premedication (steroids, antihistamines) is recommended.
Infections – Increased risk of respiratory and herpes infections; avoid live vaccines.
Hepatitis B Reactivation – Screen for HBV before starting; monitor closely.
Immunosuppression – CD20+ B-cell depletion may increase infection risk; monitor immunoglobulin levels.
Malignancy Risk – Potential link to breast cancer; monitor for symptoms.
Pregnancy & Contraception – Avoid during pregnancy; use contraception during treatment and 6 months after.

Vaccination – Live vaccines contraindicated; inactivated vaccines may be less effective.

Possible Side Effects of Ocrevus 300mg Injection

Common Side Effects:

Infusion Reactions (most frequent): Fever, chills, rash, itching, nausea, headache, dizziness, shortness of breath, or throat irritation during or after infusion.

Infections: Increased risk of upper and lower respiratory infections, herpes infections, urinary tract infections.

Serious Side Effects:

Hepatitis B Reactivation: Can be life-threatening; requires screening before treatment.

Severe Infusion Reactions: Anaphylaxis, hypotension, or difficulty breathing may occur.

Weakened Immune System: Increased risk of severe infections due to B-cell depletion.

Progressive Multifocal Leukoencephalopathy (PML): A rare, fatal brain infection caused by the JC virus; monitor for neurological symptoms.

Cancer Risk: Increased incidence of breast cancer; other malignancies possible.

Other Side Effects:

Fatigue

Skin infections

Joint pain

Low white blood cell count (neutropenia)

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Ocrevus 300mg/10ml Injection (Ocrelizumab)

Product Description

Description

How Does Ocrevus 300mg Injection Work?

How Should You Take Ocrevus 300mg Injection?

Additional Details

Uses of the Ocrevus 300mg Injection

Recommended Dosage of Ocrevus 300mg Injection

Warnings and Precautions of Ocrevus 300mg Injection

Possible Side Effects of Ocrevus 300mg Injection

Customer Reviews

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