What is a Niranib 100mg Capsules?

Niranib 100mg Capsules are a prescription medication used primarily in the treatment of certain types of cancer, including ovarian, fallopian tube, and peritoneal cancers. They belong to a class of drugs called PARP inhibitors (Poly ADP-Ribose Polymerase inhibitors).

Can I Buy Niranib 100mg Capsules Online in Pakistan?

Yes, you can buy Niranib 100mg Tablets from Jasmeds, which is a reliable provider of wellness medicines in Pakistan offering 24/7 delivery service.

What Should You Do If You Take an Overdose of Niranib 100mg Tablet?

Here are some general guidelines for what to do in case of an overdose: Stay calm and do not panic. If the person is unconscious, check for breathing and a pulse. If they are not breathing, begin CPR. If the person is conscious but experiencing symptoms, such as dizziness, nausea, or vomiting, monitor them closely and seek medical attention if their condition worsens. Have the medication container or packaging available to show to medical professionals. This will help them identify the substance involved.

Does Niranib 100mg Capsule Affect Kidney Patients?

Yes, Niranib 100mg Capsule Affect Kidney Patients. Here's why: Niranib, like other NSAIDs, can sometimes cause side effects that affect the kidneys, such as: Niranib can decrease blood flow to the kidneys, which can impair their ability to filter waste products from the blood. In some cases, Niranib can cause a sudden decrease in kidney function, known as acute kidney injury.

Can I Take Niranib 100mg Tablet Before Driving?

No, It is generally not advisable to drive after taking Niranib 100mg tablets.

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Niranib 100mg Capsules (Niraparib)

Niranib 100mg capsules contains (Niraparib) which is now available in Pakistan at Jasmeds. The price range of the Niranib 100mg Capsules is Rs 65,000 to Rs 80,000/-.

Product Description

Brand: Niranib
Form: Capsules
Packet Size: 30’s Tablets
Active ingredient: (Niraparib)
Manufacturer: Everest
Treatment: Peritoneal Cancer

₨ 75,000

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Description

How Does Niranib 100mg Capsules Work?

Niranib 100mg Capsules work by targeting and inhibiting an enzyme called poly (ADP-ribose) polymerase (PARP). This enzyme plays a crucial role in repairing damaged DNA in cells. By blocking PARP, Niranib prevents cancer cells from repairing their DNA, leading to cell death.

This mechanism is particularly effective in cancers associated with BRCA1 or BRCA2 gene mutations, as these cancer cells already have a reduced ability to repair DNA damage.

If you have been prescribed Niranib, its action helps slow the progression of ovarian, fallopian tube, or peritoneal cancer. Research has shown that patients taking PARP inhibitors like Niranib can experience a significant increase in progression-free survival compared to those not using the medication.

How Should You Take Niranib 100mg Tablet?

To take Niranib effectively, follow these guidelines:

Take one capsule of Niranib 100mg daily, or as directed by your doctor. Do not alter the dosage without consulting your healthcare provider.

Swallow the capsule whole with water, preferably at the same time each day to maintain consistent drug levels in your body. You can take it with or without food.

Do not crush, chew, or open the capsule, as this may affect the drug’s efficacy.

If you miss a dose, take it as soon as you remember unless it’s close to your next scheduled dose. In that case, skip the missed dose and continue your regular schedule. Do not double up on doses.

You should avoid consuming grapefruit or grapefruit juice while taking Niranib, as it may interfere with how the medication works.

Uses of the Niranib 100mg Capsules

Niranib 100mg Capsules are primarily used for the treatment of ovarian, fallopian tube, and peritoneal cancer.

You may be prescribed Niranib 100mg as a maintenance therapy if you have responded well to prior chemotherapy. It is particularly effective in cases where the cancer is linked to BRCA1 or BRCA2 gene mutations. Clinical studies have shown that Niranib significantly delays cancer progression, offering an improved progression-free survival period for patients.

Recommended Dosage of Niranib 100mg Capsules?

The typical recommended dosage of Niranib 100mg Capsules is one capsule taken orally once daily.

Warnings and Precautions

When taking Niranib 100mg tablets, it is crucial to be aware of the following warnings and precautions to ensure safe use:

Bone Marrow Suppression: Niranib may cause a decrease in blood cell counts, including red and white blood cells and platelets. Regular blood tests are necessary to monitor for anemia, infection risk, or bleeding tendencies. Inform your doctor if you experience fatigue, fever, or unusual bruising.

Gastrointestinal Issues: Nausea, vomiting, diarrhea, or loss of appetite may occur. Stay hydrated and consult your doctor if symptoms persist or worsen.

Liver Function: Niranib can affect liver enzymes. Your doctor will monitor your liver function through blood tests. Report symptoms like yellowing of the skin or eyes (jaundice) or dark urine immediately.

Pregnancy and Breastfeeding: Do not take Niranib if you are pregnant, planning to become pregnant, or breastfeeding, as it may harm the baby. Use effective contraception during treatment and for a specified period after stopping the medication, as advised by your doctor.

Drug Interactions: Avoid grapefruit and grapefruit juice, as they can interfere with how Niranib is metabolized. Inform your doctor about all medications, supplements, or herbal products you are taking to prevent harmful interactions.

Allergic Reactions: If you experience symptoms like rash, itching, swelling, severe dizziness, or trouble breathing, stop taking Niranib and seek medical attention immediately.

Kidney Function: Patients with impaired kidney function should use Niranib cautiously. Dosage adjustments may be required based on kidney health.

Driving or Operating Machinery: Niranib may cause fatigue or dizziness. Avoid driving or operating heavy machinery if you feel unwell or unable to focus.

Possible Side Effects of Niranib 100mg Capsules

Niranib 100mg Capsules may cause side effects, which vary in severity and frequency among individuals. It’s important to monitor your health and report any unusual symptoms to your doctor. Here are the possible side effects:

Common Side Effects:

Nausea and Vomiting: You may feel nauseous or experience vomiting, particularly during the initial days of treatment. Taking the capsule with food might help reduce these effects.

Fatigue: Feeling tired or weak is common. Rest and adequate hydration can help manage fatigue.

Anemia: A decrease in red blood cells may cause symptoms like shortness of breath, dizziness, or pale skin.

Loss of Appetite: Reduced appetite may lead to unintentional weight loss. Maintaining a balanced diet is essential.

Less Common but Serious Side Effects:

Diarrhea or Constipation: Changes in bowel habits may occur. Stay hydrated and consult your doctor for appropriate remedies.

Headache: You might experience mild to moderate headaches. Over-the-counter pain relief can be used if recommended by your doctor.

Serious Side Effects (Seek Immediate Medical Attention)

Severe Anemia or Low Platelet Count: Signs include extreme fatigue, easy bruising, or prolonged bleeding.

Signs of Infection: Fever, chills, or persistent sore throat could indicate a low white blood cell count.

Liver Problems: Watch for symptoms like yellowing of the skin or eyes (jaundice) and dark urine.

Allergic Reactions: Rash, itching, swelling, severe dizziness, or trouble breathing require urgent medical care.

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