Niranib 100mg Capsules (Niraparib)

Niranib 100mg Capsules are a prescription medication used primarily in the treatment of certain types of cancer, including ovarian, fallopian tube, and peritoneal cancers. They belong to a class of drugs called PARP inhibitors (Poly ADP-Ribose Polymerase inhibitors).

Yes, you can buy Niranib 100mg Tablets from Jasmeds, which is a reliable provider of wellness medicines in Pakistan offering 24/7 delivery service.

Here are some general guidelines for what to do in case of an overdose:

Stay calm and do not panic.

If the person is unconscious, check for breathing and a pulse. If they are not breathing, begin CPR.

If the person is conscious but experiencing symptoms, such as dizziness, nausea, or vomiting, monitor them closely and seek medical attention if their condition worsens.

Have the medication container or packaging available to show to medical professionals. This will help them identify the substance involved.

Yes, Niranib 100mg Capsule Affect Kidney Patients. Here’s why:

Niranib, like other NSAIDs, can sometimes cause side effects that affect the kidneys, such as:

Niranib can decrease blood flow to the kidneys, which can impair their ability to filter waste products from the blood. In some cases, Niranib can cause a sudden decrease in kidney function, known as acute kidney injury.

No, It is generally not advisable to drive after taking Niranib 100mg tablets.

Niranib (Niraparib) treatment should continue until disease progression or unacceptable toxicity occurs. There is no specific duration for which it can be taken without any side effects, as side effects can vary from person to person and may develop at any point during treatment.

It is crucial to consult with your doctor or healthcare provider for personalized advice regarding the duration of Niranib treatment and potential side effects. They can monitor your condition and adjust the treatment as needed. Do not stop taking Niranib without consulting your doctor.

If you miss a dose of Niranib, take the next dose at your regularly scheduled time. Do not take a double dose to make up for the missed dose.

If you vomit after taking a dose, do not take another dose at that time. ¹ Continue with your next scheduled dose.

It is important to maintain your regular dosing schedule as prescribed by your doctor for the best results. If you have any concerns or frequently miss doses, it’s best to discuss this with your doctor or pharmacist.

Store Niranib capsules in a closed container at room temperature, away from heat, moisture, and direct light.  Keep them out of the reach of children and pets. Do not store them in the bathroom. Do not keep outdated or no longer needed medicine. Ask your healthcare professional about the proper way to dispose of any unused medication.

No, pregnant women should not take Niranib.

Niranib can harm an unborn baby and may cause loss of pregnancy (miscarriage). Women who can become pregnant should have a pregnancy test before starting treatment and should use effective birth control during treatment and for at least 6 months after the last dose.  

Manage Niranib side effects by:

Nausea/Vomiting: Taking at bedtime, eating small meals, staying hydrated, considering anti-nausea medication with doctor’s advice.  
Fatigue: Balancing rest and activity.  
Constipation: Increasing fiber and fluids.
Insomnia: Maintaining a regular sleep schedule.  
Low Blood Cell Counts: Avoiding infections and injuries, reporting any signs to your doctor.

While taking Niranib, you should expect to get blood tests frequently, especially at the beginning of your treatment. Here’s a breakdown of the typical schedule:

Weekly for the first month: Your doctor will likely order complete blood counts (CBCs) every week during the first month of treatment. This is to monitor for potential hematologic side effects like low blood cell counts (platelets, red blood cells, and neutrophils).

Monthly for the next 11 months: After the first month, if your blood counts are stable, the frequency will likely decrease to once a month for the next 11 months. 

Periodically thereafter: After the initial 12 months, your doctor will determine how often you need blood tests based on your individual response to the medication and any ongoing side effects.

Yes, Niranib can be used in combination with other cancer medications in certain situations. Here’s what the search results indicate: 

Bevacizumab: A phase 2 clinical trial (OVARIO) showed that the combination of Niranib and bevacizumab as maintenance therapy in advanced ovarian cancer was effective in prolonging progression-free survival without cumulative toxicity.

Etoposide: A phase 2 study evaluated the combination of oral Niranib and etoposide in patients with platinum-resistant/refractory ovarian cancer. The combination showed evidence of antitumor activity, particularly in patients with BRCA mutations, homologous recombination deficiency, or primary platinum resistance.

Anti-angiogenic agents: Research suggests that combining PARP inhibitors like Niranib with anti-angiogenic inhibitors can have synergistic antitumor effects in various cancers, including ovarian cancer.

Here’s what the search results indicate:

Can be taken with or without food: Several sources explicitly state that Niranib can be taken with or without food. Food does not appear to significantly affect the absorption of the medication.

Bedtime administration for nausea: If you experience nausea, taking Niranib at bedtime might help manage this side effect.

No specific food interactions mentioned: The search results do not highlight any specific foods or beverages that you should avoid while taking Niranib.