Fungizone (amphotericin B) contains amphotericin B, an antifungal polyene antibiotic obtained from a strain of Streptomyces nodosus.Each vial contains a sterile, nonpyrogenic, lyophilized cake (which may partially reduce to powder following manufacture) providing 50 mg amphotericin B and 41 mg sodium desoxycholate with 20.2 mg sodium phosphate as a buffer. Crystalline amphotericin B is insoluble in water; therefore, the antibiotic is solubilized by the addition of sodium desoxycholate to form a mixture which provides a colloidal dispersion for intravenous infusion following reconstitution.
At the time of manufacture the air in the vial is replaced by nitrogen.
FUNGIZONE 50MG INJECTION (AMFORTERISIN B) works by slowing the growth of fungi that cause infection.
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