Dostinex 0.5mg 8’s Tablet (Cabergoline)

How Does Dostinex 0.5mg Tablet Work? 

Dostinex 0.5mg Tablets (cabergoline) work primarily by acting as a dopamine receptor agonist, specifically targeting the D2 dopamine receptors in the pituitary gland. Here’s a concise breakdown of its mechanism of action:  

Dopamine Receptor Activation: Cabergoline stimulates D2 receptors on lactotroph cells in the anterior pituitary gland, leading to a direct inhibition of prolactin secretion. This results in decreased levels of prolactin in the bloodstream.

Prolactin Regulation: By reducing prolactin levels, cabergoline alleviates symptoms associated with hyperprolactinemia, such as irregular menstrual cycles and unwanted lactation.

Long-acting Effects: Cabergoline is noted for its long duration of action, allowing for less frequent dosing compared to other treatments for elevated prolactin levels.

How Should You Take Dostinex 0.5mg Tablets?

Dostinex 0.5mg Tablets (cabergoline) should be taken as follows:

Initial Dose: Typically, the starting dose is 0.5 mg per week, which can be taken as half a tablet (0.25 mg) twice a week (e.g., on Monday and Thursday).

Adjustment: The dosage may be gradually increased by 0.5 mg per week at monthly intervals, based on the patient’s response and serum prolactin levels. The usual therapeutic range is between 0.25 mg and 2 mg per week, with a maximum of 4.5 mg per week.

Take the tablets with or after food to reduce the risk of gastrointestinal side effects such as nausea.

Swallow the tablets whole with a glass of water.